These two powders are very interesting, and I use them both when working up hotties in the +.400" bores.
Very careful testing required; one will always do better than the other, whether it be lower deviations, better accuracy, or higher speed.
In the 41 I found through my gun that H110 was 'the one'; your results may vary.
(And don't forget to throw Vihta's N110 into the mix.....)
"all my ammo is mostly retired factory ammo"