There is certtainly a possibility that depriming would set off the primer. However, I have deprimed live primers on various occassions and have never had one go off.
I always go very slow when I do it. Wear safety lenses/glasses when you do it to be safe.
Ecclesiastes 12:13 *¶Let us hear the conclusion of the whole matter: Fear God, and keep his commandments: for this is the whole duty of man.
14 *For God shall bring every work into judgment, with every secret thing, whether it be good, or whether it be evil.